About Us
DualityBio

Duality Biotherapeutics is a clinical-stage biotech company dedicated to the discovery and development of next-generation ADC to treat cancer and autoimmune diseases. DualityBio has successfully built several cutting-edge ADC technology platforms with global intellectual property rights. Leveraging a robust pipeline, DualityBio is conducting multiple global clinical trials across 17 countries, has enrolled over 2000 patients for multiple clinical-stage ADC candidates.

Additionally, DualityBio have established strategic collaborations with global MNCs and leading biotech innovators. As a global ADC powerhouse, DualityBio is developing "Super ADCs," including bispecific ADCs, novel-payload ADCs, and autoimmune ADCs. 

  • 2000+
    Patients enrolled
  • 17+
    Countries MRCTs
  • 4
    Versatile Platforms
  • 7
    Clinical Stage Assets
  • 6
    landmark BD deals
  • US$6bn+
    Total Deal Value
Story Of Duality
2025
2024

HER2 ADC Global Phase 3 trial FPI in HER2-Low BC

HER2 ADC (DB-1303) Phase 3 trial FPI in HER2+ BC

B7-H3 ADC (DB-1311) Global Phase 2 trials FPI

NMPA BTD for HER2 ADC (DB-1303)

FDA FTD & ODD for B7-H3 ADC (DB-1311)

FDA FTD for TROP2 ADC (DB-1305)

B7-H3 x PD-L1 BsADC (DB-1419) FDA IND approval

First-in-human study for Autoimmune ADC (DB-2304)

B7-H3 ADC (DB-1311) data read-out

2023

DB-1303 FDA Fast Track Record Designation

DB-1303 Ph2 Clinical Trail 1st Patient in

DB1310 FDA IND Approval

DB1311 FDA IND Approval

DB1310 China IND Approval

DB1311 China IND Approval

Entered into an exclusive licensing and collaboration agreement with BioNTech, licensing out global rights to develop, manufacture, and commercialize of DB-1303 and DB-1311.

Lisensed BeOne global rights of DB-1312.

Licensed BioNTech the global rights to DB-1305, excluding the Greater China region

DB-1303 FDA Breakthrough Therapy Designation

2022

DB-1303 Ph1 Clinical Trail 1st Patient in

DB-1303 China IND Approval

DB-1305 FDA IND Approval

DB-1305 China IND Approval

30 million USD B+ Round Financing

Suzhou R&D Center Launching

Successfully selected as a "Gazelle Cultivation Enterprise" in Suzhou

2021

80 million USD B Round Financing

DB-1303 FDA IND Approval

2020

Building DITAC TOP1i Platform

5 Million USD Seed Financing

22.5 Million USD

Thesmall molecule toxin ADC platform submitted the priority patent application. 

Dr. Zhongyuan Zhu has been awarded the Leading Talent in Science and Technology of Suzhou 

2025
2024
2023
2022
2021
2020
Leadership Team
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Board Of Directors
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Scientific Advisory Board
Antoine Yver, M.D., MSc
Scientific Advisory Board

■  Former EVP, Global Head of Oncology R&D and Chair of the Cancer Enterprise at Daiichi Sankyo

■  Former SVP, Head Oncology Global Medicines Development at AstraZeneca

■  Successfully developed of ENHERTU, TAGRISSO and LYNPARZA


Dr. Pasi A. Jänne
Scientific Advisory Board

■  Professor of Medicine at Harvard Medical School

■  Thoracic Medical Oncologist at Dana-Farber Cancer Institute

■  Leading PI of early clinical development of Patritumab Deruxtecan (HER3-DXd)



Honor Of Duality
Champion of "Best New Drug Development Enterprise" at the 15th World ADC Awards
Biocentury BayHelix 2023 Company of the year
Annual cooperation with R&D clients